SAN FRANCISCO nike air max 90 womens nz , May 22 (Xinhua) -- A biochemical self-destruct trigger, a protein called RIPK3, found in many other types of cells appears to guard the lives of brain cells during infection with West Nile virus.
RIPK3 is better known for activating a certain type of cell death during infection or other damaging events in other parts of the body. The death of infected cells in this manner is a protective mechanism that helps the body eliminate the infection.
In a recent Cell paper on how brain cells ward off West Nile virus, University of Washington (UW) researchers who led the research say the chemical pathway doesn't have to sacrifice brain cells to destroy the viruses and recruit the body's defenses against infection, and can preserve the brain's nerve cells cheap nike air max 90 free shipping , or neurons, by using an alternative approach to summon protection.
During a West Nile virus infection, the activation of RIPK3 in brain cells doesn't cause them to die. That is because its signaling within the central nervous system is not the same as in cell types elsewhere in the body. Its brain-specific role implies that there are central nervous system functions for RIPK3 not observed in other tissues.
"There is something special about neurons, perhaps because they are non-renewable and too important to undergo cell death," said Andrew Oberst cheap nike air max 90 online , assistant professor of immunology at the University of Washington School of Medicine and senior author on the paper.
RIPK3 responds to the presence of West Nile virus in the brain by placing an order for chemokines, the researchers observed.
The lead author of the paper, Brian Daniels, a UW Medicine postdoctoral fellow in immunology, explained that these chemicals underlie a successful ousting of West Nile virus. Chemokines attract an influx of infection-fighting white blood cells.
These efforts contribute to the clearance of the virus from the brain cheap nike air max 90 sale , but not by directly stopping replacement virus from reproducing within brain cells. Instead, the brain tissue undergoes a kind of inflammation that restricts the West Nile virus infection. "RIPK3 acts as part of the milieu of signals that support anti-viral inflammation in the brain," said Daniels.
In a different cell type, such as a fibroblast, the entry of a West Nile virus would result in the cell initiating its own demise.
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BEIJING, May 23 (Xinhua) -- A much-anticipated bill to regulate the parking of Beijing's millions of cars will be submitted to the municipal legislature this year, its drafters said.
The rule will promote the use of automated parking meters to discourage unlicensed parking assistants who have become a source of complaints from car-owners. It will also encourage residential communities, businesses and government compounds to open their parking spaces to the public.
More than 1,300 suggestions have been received since members of the public were invited to give their opinions in April cheap nike air max 90 wholesale , said Jiang Yingming, a city government official in charge of the legislation.
Like many Chinese cities, Beijing has experienced an explosive growth in the number of private cars thanks to rising living standards and dropping car prices. But parking has become a headache for most car-owners as city planners did not foresee the boom of automobiles.
LOS ANGELES, July 24 (Xinhua) -- Crews rescued 17 hikers stranded by floods in a canyon near Tucson, a city in southern Arizona cheap nike air max 90 mens , 800 km southeast of Los Angeles in the United States.
According to the Pima County Sheriff's Department (PCSD), search and rescue deputies, fire crews and a rescue team worked from Sunday night to early Monday to retrieve the 17 hikers, including a 4-year-old boy, from the canyon.
Before that cheap nike air max 90 womens , police received a call for help shortly after 5:30 p.m. local time on Sunday (0030 GMT Monday).
The last two hikers clinging to tree branches overnight were lifted Monday by a helicopter from a rocky, narrow and flood-running creek to safety, as is shown in the video clips posted by rescue crews on Twitter.
Nine people from an extended family were killed in a flash flooding in a scenic canyon in Arizona last week.
Monsoon rains, a regular summertime occurrence in Arizona, often lead to swift and deadly flash floods as rainwater rushes down the mountains into dry canyons or peaceful creeks.
On Monday cheap air max 90 free shipping nz , the PCSD warned tourists of the danger of flash flooding in mountains on its official website.
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BEIJING， March 29 (Xinhua) -- It was the must have item for venture capitalists -- a portfolio containing Chinese web startups. Now， the tides have turned and the next big thing appears to be the sharing economy.
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